complex systems http://popups.lib.uliege.be/1373-5411/index.php?id=2240 Index terms fr 0 The Decision of a Goal-Directed Behavior Problem in a Class of Systems Described by one-to-one Transformations http://popups.lib.uliege.be/1373-5411/index.php?id=2239 In the Theory of Systems attention is traditionally directed to the problems of control, diagnostics and correction of complex systems behavior. At present a devices and technologies are very complicate and the problem of generating goal-directed behavior is one of prior. In the general case (that is, for an arbitrary complex system) the problem of generating goal-directed behavior is algorithmically insoluble, but it can be solved by imposing certain restrictions on the system behavior. Approach to a decision of referred above problem in class of intellectual systems described by one-to-one transformations (without loss of information) is offered in this scientific work. Tue, 30 Jul 2024 15:26:23 +0200 Thu, 10 Oct 2024 16:37:17 +0200 http://popups.lib.uliege.be/1373-5411/index.php?id=2239 Empirical Mediation of the Primary Mechanism Initiating Protein Conformation in Prion Propagation http://popups.lib.uliege.be/1373-5411/index.php?id=3725 Transmissible prion based spongiform encephalopathies propagate by conformational change of the prion's protein, PrP structure. An experimental design, relying on the utility of a new fundamental teleological action principle inherent in the topological geometry of a covariant polarized Dirac vacuum putatively driving self-organization in all autopoietic complex living systems, is developed to elucidate the fundamental nature of this conformational change. Further, PrP propagation is considered a mechanical action that can be described by 'interactive computational modes' of 'topological switching' driven by incursive oscillations occurring in the bioenergetics of the prions physical chemistry when improperly coupled to the long-range coherence of the noetic action. The experimental apparatus, a multi-level interferometer, is designed to focus this noetic field in a manner that simulates the mechanism driving PrP conformation to pathological form. Thu, 26 Sep 2024 11:23:24 +0200 Tue, 08 Oct 2024 13:54:34 +0200 http://popups.lib.uliege.be/1373-5411/index.php?id=3725